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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR1
All Species:
21.52
Human Site:
S399
Identified Species:
39.44
UniProt:
O43613
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43613
NP_001516.2
425
47536
S399
R
S
S
A
S
H
K
S
L
S
L
Q
S
R
C
Chimpanzee
Pan troglodytes
XP_524646
425
47381
S399
R
S
S
A
S
H
K
S
L
S
L
Q
S
R
C
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
T356
I
H
S
E
V
S
V
T
F
K
A
K
K
N
L
Dog
Lupus familis
XP_544446
502
56267
S476
R
S
S
A
S
H
K
S
L
S
L
H
S
R
C
Cat
Felis silvestris
Mouse
Mus musculus
P58307
416
46748
S390
G
S
S
A
R
H
K
S
L
S
L
Q
S
R
C
Rat
Rattus norvegicus
P56718
416
46781
S390
S
S
S
A
R
H
K
S
L
S
L
Q
S
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
L387
R
S
T
S
Q
K
S
L
S
L
Q
S
K
F
T
Chicken
Gallus gallus
Q9DDN6
385
43491
A360
I
H
P
E
V
S
A
A
F
K
A
R
K
K
L
Frog
Xenopus laevis
P70031
453
51139
K420
G
T
F
S
S
C
I
K
P
C
R
N
F
R
D
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
S399
Q
R
A
R
G
R
T
S
T
D
S
R
K
S
L
Tiger Blowfish
Takifugu rubipres
NP_001092118
426
48303
T394
N
S
L
D
R
K
P
T
S
R
R
V
N
H
I
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120335
399
45437
A374
G
L
C
Y
F
N
S
A
V
N
P
L
I
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
S422
R
D
S
T
A
I
T
S
T
A
S
R
R
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
25.8
78.8
N.A.
91.7
91.5
N.A.
81.8
26.5
24.5
61.1
26
N.A.
35.7
N.A.
32.9
Protein Similarity:
100
96.4
46.3
81
N.A.
93.8
93.6
N.A.
85.6
47.5
47.4
73.1
42.9
N.A.
51.7
N.A.
51.5
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
13.3
0
13.3
6.6
6.6
N.A.
0
N.A.
20
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
86.6
N.A.
26.6
20
26.6
26.6
20
N.A.
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
39
8
0
8
16
0
8
16
0
0
8
0
% A
% Cys:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
39
% C
% Asp:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
16
0
0
0
8
8
0
% F
% Gly:
24
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
16
0
0
0
39
0
0
0
0
0
8
0
8
0
% H
% Ile:
16
0
0
0
0
8
8
0
0
0
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
16
39
8
0
16
0
8
31
8
0
% K
% Leu:
0
8
8
0
0
0
0
8
39
8
39
8
0
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
8
0
8
8
8
8
% N
% Pro:
0
0
8
0
0
0
8
0
8
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
8
31
0
0
8
% Q
% Arg:
39
8
0
8
24
8
0
0
0
8
16
24
8
47
0
% R
% Ser:
8
54
54
16
31
16
16
54
16
39
16
8
39
8
0
% S
% Thr:
0
8
8
8
0
0
16
16
16
0
0
0
0
0
8
% T
% Val:
0
0
0
0
16
0
8
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _